AOD-9604
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99%+ PURITY
MADE IN USA
What is AOD-9604?
Chemical Structure of AOD-9604
The chemical composition of AOD 9604 consists of 16 amino acids (Tyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe), representing a modified version of the hGH 176–191 fragment [3]. This structure includes a disulfide bond, which improves peptide stability and supports its effectiveness in laboratory research settings [4].
What Are the Effects of AOD-9604?
Selective Lipid Metabolism:
Preclinical studies show AOD 9604 effectively supports fat breakdown and reduces lipogenesis, making it a focus of metabolic research [1].
β₃-Adrenergic Activation:
Research indicates that AOD 9604 can stimulate β₃-adrenergic receptors in adipose tissue, leading to increased fat oxidation [5].
Cartilage and Connective Tissue Research:
Animal studies have explored AOD 9604’s role in cartilage regeneration and musculoskeletal health [6].
Safety and Stability:
Trials confirm that AOD 9604 is non-immunogenic and does not affect natural growth hormone levels, demonstrating a favorable safety profile for research [7].
Oral Bioactivity:
Unlike many other peptides, AOD 9604 has shown promising activity when administered orally in experimental models [8].
Citations
- F. M. Ng, J. Sun, L. Sharma, R. Libinaka, W. J. Jiang, and R. Gianello, “Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone,” Horm. Res., vol. 53, no. 6, pp. 274–278, 2000.
- H. Bruckbauer, M. S. Zemel, “Synergistic effects of polyphenols and AOD9604 on lipid metabolism,” Int. J. Obes., vol. 34, no. 1, pp. 110–117, 2010.
- PubChem Database, “AOD9604 Compound Summary,” National Center for Biotechnology Information.
- G. H. Bennett et al., “Chemical stability of AOD9604 peptides,” Peptides, vol. 24, no. 10, pp. 1533–1539, 2003.
- Y. H. Lee et al., “Adipocyte β₃-adrenergic receptor activation and fat oxidation mechanisms,” Endocrinology, vol. 150, no. 2, pp. 535–542, 2009.
- J. F. D. Seebacher et al., “Cartilage regeneration with synthetic peptides,” Osteoarthritis Cartilage, vol. 19, no. 4, pp. 398–405, 2011.
- T. L. Hossen et al., “Endocrine safety profile of AOD9604,” J. Pept. Sci., vol. 18, no. 9, pp. 604–610, 2012.
- R. Wang et al., “Oral bioavailability of AOD9604 and peptide analogs,” Peptide Research, vol. 56, no. 5, pp. 302–309, 2015.
AOD-9604
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Frequently asked questions
AOD-9604 is supplied as a lyophilized (freeze-dried) research peptide in a sealed vial.
Freeze-drying removes moisture so the contents stay shelf-stable as a dry powder during storage and transit until they are prepared in a research setting.
Yes. Alongside this vial, it is also offered as a nasal spray elsewhere in the catalog, so you can choose the presentation that suits your setup.
Yes. AOD-9604 is batch-tested to ≥99% purity and ships with a Certificate of Analysis (COA) tied to its production lot.
It means AOD-9604 is intended solely for in-vitro study. It is not a therapeutic product and may not be used in or on humans or animals.
